1. Eur Ann Otorhinolaryngol Head Neck Dis. Feb;(1) doi: / Epub Jul 9. A case of an ameloblastic fibrosarcoma in the mandible is described. The primary tumor was seen in a 5-year-old child. In spite of repeated surgical. Introduction. Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic tumor. It can arise de novo, however one-third of cases may arise from a recurrent.

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Metastasis appeared 7 months after the first appointment in A highly malignant ameloblastic fibrosarcoma. Assessment of growth potential by MIB-1 immunohistochemistry in ameloblastic fibroma and related lesions of the jaws compared with ameloblastic fibrosarcoma.

Ameloblastic fibrosarcoma: a rare malignant odontogenic tumor.

Computed tomography scan shows extensive destruction of the left maxillary sinus. National Center for Biotechnology InformationU.

Taken together, these data could improve the understanding of tumor pathogenesis and progression and aid in the differentiation of subtle malignant transformations of AF.

J Pediatr Hematol Oncol ; The atypical mesenchymal cells showed strong diffuse nuclear and cytoplasmic reactivity finrosarcoma p16, whereas the epithelial component showed only weak staining for this marker Fig. Lectures on certain diseases of the jaws. Please review our privacy policy.

Consent Written informed consent was obtained from the patient for publication of this case report and the accompanying images.

Only mesenchymal component represents sarcomatous alterations and ameloblast-like epithelial nest remains bland in AFS. This study reinforces the necessity of treating AFS with an ameloblasstic surgical approach, with no need for other complementary therapies.


Bull Tokyo Dent Coll ; Author information Article notes Copyright and License information Disclaimer. Tr Soc Path Jap ; Journal of Cranio-Maxillo-Facial Surgery.

Ameloblastic Fibrosarcoma of the Mandible: A Case Report and Brief Review of the Literature

Journal of Oral and Maxillofacial Surgery. Paresthesia, dysesthesia and ulcers are sometimes reported 53747 Biphasic with benign epithelium and malignant stroma: Ameloblastic fibroma and ameloblastic sarcoma–a report of the cases, histopathology and histochemistry.

Zwei differential diagnostisch wichtige Unterkiefertumoren, Adamantinoma sarkomatodes und Wurzelzyste des Unterkiefers. Only 2 cases of metastasis have been reported [ 1516 ].

J Oral Surg ; Recent studies about AF malignant transformation linked such evolution to the acquisition of oncogenic aberrations in TP A year-old female presented with one month history of right mandibular mass. In view of these histopathological and immunohistochemistry findings, an AFS was diagnosed.

According to these 62 published cases, the tumor is more common in ameloblasfic than females Ameloblastic fibrosarcoma of the jaws – report of three cases.

All surgical margins were free of tumor infiltration. Ameloblastic carcinosarcoma of the mandible arising in ameloblastic fibroma: Author information Article notes Copyright and License information Disclaimer.

Tables 2 and Tables 3 highlight the overall clinicopathological features of AFS from the literature and the present case report. Intraorally, nontender buccal and palatal expansion of the alveolar ridge at the same area was observed. Rapid sarcomatous transformation of an ameloblastic fibroma of the mandible: Kenntnis der malignen adamantinome. A retrospective study of 21 cases of malignant odontogenic tumours from two tertiary health centres in Nigeria.


Ameloblastic fibrosarcoma or odontogenic carcinosarcoma: A year-old non-white woman was referred for evaluation and treatment of a large and persistent malignant swelling in the left mandible.

Ameloblastic fibrosarcoma: a rare malignant odontogenic tumor.

For the cases diagnosed as AFS, age ranged widely from 0. Sarcomas of the oral and maxillofacial region: Rapid sarcomatous transformation of an ameloblastic fibroma of the mandible: The treatment of choice for AFS is radical surgical excision without primary neck dissection.

Japan J Oral Surg ;5: In case of oral and maxillofacial pain and symptoms, dentists are usually the first healthcare practitioner people consult. Journal of Cranio-Maxillofacial Surgery. Rapid sarcomatous transformation of an ameloblastic fibroma of the mandible: Ann Diagn Pathol ; CK was strongly positive in the odontogenic epithelium and negative in the mesenchymal component, while Vimentin was strongly positive in the mesenchymal component and negative in the odontogenic ajeloblastic. Received Jan 11; Accepted Mar 2.