Adenomatoid odontogenic tumor (AOT), a benign (hamartomatous) lesion of odontogenic origin, is an uncommon tumor which affects mainly. Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. To acquire additional. Adenomatoid odontogenic tumor is a hamartomous benign neoplasia of odontogenic origin. It appears mostly in young patients and females, the maxillary.

Author: Kanris Grosho
Country: Laos
Language: English (Spanish)
Genre: Sex
Published (Last): 13 July 2011
Pages: 61
PDF File Size: 8.24 Mb
ePub File Size: 9.98 Mb
ISBN: 169-8-33893-325-2
Downloads: 89185
Price: Free* [*Free Regsitration Required]
Uploader: Tomuro

There was a problem providing the content you requested

The adenomatoid odontogenic tumor: The former odoontogenic immunohistochemically positive for laminin, therefore, representing substance of the basal membrane. This article discusses the surgical management of an AOT in the maxilla in paediatric patient. In the solid nodules, cells were ovoid and cylindrical, the latter outlining duct-like structures, which contained homogeneous eosinophilic material in the center. Two thirds of the cases are found in adnomatoid.

Acta Pathol Microbiol Scand. June 09, Accepted: Small cuboid or polyhedrical cells formed peripheral cords that sometimes seemed to fold and overlap, forming compact sheets. Adenomatoid odntogenic tumor associated with dentigerous cyst in posterior maxilla: It should be enucleated along with the associated impacted tooth and simple curettage [ 26 ].

The maxillary arch is the predominant site of occurrence, being almost adenomaroid as frequent as that of the mandible, and the anterior part of the jaw is more frequently involved than the posterior part.

This material may stain for amyloid [ 3 tumoe, 10 ]. They seldom exceed 3. Adenomatoid odontogenic tumour, extra follicular, impacted canine. AOT is frequently asymptomatic and is revealed during a routine radiographic examination or when radiographs are made to determine why a tooth has not erupted [ 310 ].

In this case, AOT was associated with the lateral maxillary incisor.


Few studies in the literature have used the immunohistochemistry technique to analyze AOTs. In stafne reported first series of AOT under the title epithelial tumors associated with developments cyst of maxilla. Laminin was clearly present adenoamtoid the luminal surface of the adenomatoid structures and in the lighter eosinophilic intercellular deposits, either focal or linear, which is compatible with the surface of the reduced enamel epithelium during the protective stage of amelogenesis.

The surgical specimen may be solid or cystic. Marx RE, Stern D. Data on reported cases of adenomatoid odontogenic tumor arising from a dentigerous cyst till now in the literature Click here to view. Odontogenic neoplasms; Adenomatoid odontogenic tumor; Immunohistochemistry.

Variants of the adenomatoid odontogenic tumor with a note on tumor origin. The lumen may be empty or contain amorphous eosinophilic adenomatoiid. PCNA results in the REE were as expected, with expression restrict to the basal or suprabasal cells or cells scattered in areas in which subepithelial inflammation was present.

Adenomatoid odontogenic tumor, an uncommon tumor

Adenomatoid odontogenic tumor — hamartoma or odontotenic neoplasm: J Oral Pathol Med ; The issue of its nature being neoplastic or hamartomatous is still qdenomatoid of diverging opinions, generally based on clinical observations and little scientific evidence. J Nat Sci Biol Med. Herewith, we present the report of four unusual cases of AOT located in the mandible, with an emphasis on radiographic findings and on pathologic correlation, and on reviewing the existing literature on this tumor.

Adenomatoid odontogenic tumour adenoameloblastoma. Adenomatoid odontogenic tumor associated with dentigerous cyst in posterior maxilla: There is no doubt about the AOT origin from the odontogenic epithelium; however the cell directly involved in the pathogenesis is still under discussion.

The underlying connective tissue was fibrous, thick, with extensive areas of hemorrhage and discrete inflammatory mononuclear infiltrate.

In tooth impactions next to the alveolar ridge, the tumor could occasionally involve the gingiva during or after the eruption process, which would justify the peripheral variant.


The buccal cortex was expanded, and the surface of the swelling was smooth with a normal color of overlying mucosa. The history revealed an orthodontic treatment started in December with a treatment plan involving extraction of teeth 34, 44, 23, and J Oral Maxillofac Pathol. The tumor was well encapsulated, and the lateral incisor was easily removed with the lesion Figure 4.

Mandibular adenomatoid odontogenic tumor: Radiographic and pathologic correlation

Nil Conflict of Interest: The evolution of this tumor was followed for 36 months before enucleation and 24 months after. Well-circumscribed radiolucent lesion same in right maxilla with impacted teeth 13 and 14, with well-defined radio-opaque border.

It should be emphasized that although AOT is very rare, careful diagnosis and adequate interpretation of clinical and radiographic findings may be helpful in arriving at a correct diagnosis. Discussion AOT usually occurs within the tooth bearing areas of jaws and often found in association with impacted teeth. We would also emphasize that the AOT could remain intraosseous or peripheral in the jaw adebomatoid, depending on the spatial position of the tumor and associated tooth.

Mostly, nonneoplastic causes of jaw swelling in a young patient are an apical cyst, dentigerous cyst, calcifying odontogenic cyst, gumor keratocyst, and central giant cell granuloma [ 310 — 12 ], whereas common neoplastic causes are an adenomatoid odontogenic tumor, unicystic ameloblastoma, calcifying epithelial odontogenic tumor CEOTameloblastic fibroma, and ameloblastic fibro-odontoma [ 31213 ]. None, Conflict of Interest: Odontogenic Tumors and allied lesions.